The problem I reported was also with RAID-5, and I have also found a problem similar to Nathan's (probably the same one) by just trying to run bonnie++ on an XFS filesystem on DM over RAID-5, even after formatting the XFS filesystem to forcibly align everything to RAID-5 stripes (64K units).
FWIW, this doesn't align _everything_ (space allocations done
through the XFS allocator are influenced, which means "most")
-- log IO is still going to be sector aligned, as are any IOs
to the four XFS allocation group header metadata structures.