not guaranteed to be precise. For example a SMI (System Management
Interrupt) could interrupt the software flow that is attempting to write
the time-stamp counter immediately prior to the WRMSR. This could mean
the value written to the TSC could vary by thousands to millions of
clocks.
Yes SMI is a disaster area for any real time activity (and many other
things ;) ), but many systems actually make little use of it, especially
once the USB is owned by the OS.
For synchronization you can retry the sync if it isn't within an
acceptable range. The odds of getting an SMI mid sync setup should be
very very low, so the odds of repeating the failure several times should
be negligible and after a few tries you could give up and assume the
hardware is buggered then fall back to HPET.